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Other notable titles include Wolf Gold and Chilli Heat.<br><br>The goal of pragmatic trials is to replicate real-life situations and achieve the highest level of validity externally. Usually, they are requested by practitioners and policymakers in order to inform their decisions. They are also a good method of determining the causal relationship between an intervention and its results. They should,  [https://maps.google.com.ar/url?q=https://writeablog.net/twistbetty4/10-tell-tale-signals-you-should-know-to-look-for-a-new-pragmatic-product 프라그마틱 플레이] however, not be used to replace explanatory studies.<br><br>The concept of pragmatism is controversial, and there are questions about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 proposed an distinction between explanation-based studies, which support the validity of a physiological or clinical hypothesis, and pragmatic trials, that inform the practice and policy decision-making. They also suggested the framework for pragmatic trials, called PRECIS.2 This tool was designed to define the features of a pragmatic trial, including recruitment, design and delivery of the intervention, and follow-up.<br><br>There is a growing trend in the number of pragmatic trials that are published. A recent Medline query using the keywords naturalistic and pragmatic, restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This is a sign that the health science community is becoming more sensitive to the subject of pragmatism. It is important to keep in mind that the majority of these trials were conducted in primary care settings.