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The other notable titles include Wolf Gold and  [https://monobookmarks.com/story17996513/what-is-the-secret-life-of-pragmatic-genuine 무료슬롯 프라그마틱] Chilli Heat.<br><br>The goal of pragmatic trials is to simulate real-life situations and achieve the highest level of validity externally. They are usually requested by practitioners and policy makers to guide their decision-making. They can also be a great method of determining the causal relationship between an intervention and its results. However, they should not be used to replace explanation studies.<br><br>The idea of pragmatism is controversial and there are doubts about whether pragmatic trials should replace tests for explanations or if they should be an addition to them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which support a physiological hypothesis or clinical hypothesis, and pragmatic trials, that inform the practice and policy decision-making. They also proposed an approach to pragmatic trials, dubbed PRECIS.2 This tool sought to define the characteristics of a pragmatic trial which includes the recruitment process, the design and implementation of the intervention, as well as monitoring.<br><br>The number of pragmatic trials is increasing. A recent Medline search using the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This is a sign that the health sciences community is becoming more sensitive to the issue of pragmatic thinking. However, it is important to keep in mind that the majority of these trials were conducted in primary care settings.