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Some of these games include bonus games that allow players to win free spins.<br><br>The company's new release Gates of Olympus takes players to the world of the ancient Greek gods and  [https://bookmarkinglive.com/story18826954/why-pragmatic-slot-experience-is-more-difficult-than-you-imagine 프라그마틱 무료체험] goddesses, where Zeus is in charge of the action. This slot game with high volatility features the Pay Anywhere option that pays players when they hit 8 or more matching symbols anywhere in the reels. It also includes an extremely lucrative Free Spins feature with multipliers that can go up to 500x bet.<br><br>Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and included participants from various geographical areas. This type of heterogeneity which is essential for a pragmatic trial to be reliable and reduce bias in results, is also necessary. Too much heterogeneity, however can result in problems with the design of the trial.<br><br>Pragmatic Play is also a major player in the live casino market, providing an extensive selection of table games like as Blackjack and Roulette in various versions. The live studios of the company in Romania and Malta offer customers an authentic experience in gambling and a wide variety of betting options via virtual. The company also hosts a variety of games that make online gambling more exciting and interactive. Some of these shows feature a live host, while others are hosted by famous personalities from the industry.<br><br>Mobile compatibility<br><br>Pragmatic Play is a new player in the world of online casinos however, it has made a name for itself by offering mobile-friendly slots. Their games are optimized for mobile devices and run on HTML5 technology. They are also certified by reputable gaming authorities to ensure transparency and fairness. 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Wolves is one of its latest releases, a 5-reel slot machine with a healthy RTP and impressive graphics. Other notable titles include Wolf Gold and Chilli Heat.<br><br>Pragmatic trials seek to replicate real-world situations and have the highest external validity. They are usually commissioned by practitioners and policy makers to inform their decision making. They are also a good method of determining the causal relationship between an intervention and its results. They should not, however be used to replace explanatory studies.<br><br>The pragmatism idea is controversial and there are doubts about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 proposed the distinction between explanation studies, which support a physiological hypothesis or clinical hypothesis, and pragmatic trials, that inform the practice and policy decision-making. They also proposed the framework for pragmatic trials, which they called PRECIS.2 This tool sought to define the elements of a pragmatic study that include recruitment, design and delivery of the intervention, and follow-up.<br><br>There is a growing increase in the number of pragmatic trials that are published. A recent Medline search using the terms naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs), yielded 34 articles, as shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. It is important to remember that the majority of these studies were conducted in primary care settings.