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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are often described as a focus on the practical aspects of designing a study which include the recruitment process and consent, adhering and the use of routinely available equipment.

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A pragmatic study that involves a variety investigators and includes participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity which is essential for pragmatic trials to be valid and to reduce bias in the results is also essential. However too much heterogeneity could result in problems with the design of the trial.

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Mobile compatibility

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Legality

Pragmatic Play is known for its top-notch games, and for offering an exceptional user experience. Its software is designed to work with mobile devices and supports different languages. It has been recognized as one of the leading casino gaming platforms despite its relatively young age. Its latest releases include Wolves 5 reel video slot with a healthful RTP and stunning graphics. Other notable games include Wolf Gold and Chilli Heat.

The purpose of pragmatic trials is to replicate real-life scenarios and to achieve the highest level of validity externally. They are usually requested by policy makers and practitioners to guide their decision-making. They can also be used to assess the causality of an intervention and its results. They should, however, not, be used to replace explanation studies.

The concept of pragmatism is controversial and there are concerns regarding whether pragmatic trials could replace tests for explanations or if they should serve as a complement to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which prove the clinical or physiological hypothesis as well as pragmatic trials, which inform the policy and practice of. They also suggested the framework for pragmatic trials, which they called PRECIS.2 This tool sought to define the characteristics of a pragmatic study, including recruitment, design and delivery of the intervention, as well as follow-up.

There is a growing increase in the number of pragmatic trials that are published. A recent Medline query using the keywords pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This indicates that the health science community is becoming more sensitive to the subject of pragmatic thinking. It is important to remember, however, that the majority were conducted in primary care settings.