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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are usually focused on the practical aspects of the study design, including recruitment and consent, adherence, and the use of standard equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which employed different investigators and included participants from different geographical regions. This type of heterogeneity, that is crucial for 프라그마틱 공식홈페이지 a pragmatic trial to be valid and reduce bias in results is also essential. However, too much heterogeneity can result in problems with the design of the trial.

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Mobile compatibility

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Pragmatic Play offers not only mobile-friendly slot machines as well as table games and live casino. Pragmatic Play is licensed by a variety of regulatory bodies which include Malta Gaming Authority and UK Gambling Commission. The games of the company are secured by top-of-the-line encryption, and its security team is available to help players with any issues.

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Legality

Pragmatic Play has earned a name for itself by providing top-quality games and an outstanding user experience. Its software is accessible on mobile devices and in a variety of languages. It has been recognized as one of the top casino gaming platforms despite its relatively young age. Wolves is one of the most recent releases, a 5-reel slot machine that has a high RTP and impressive graphics. Its other notable titles are Wolf Gold and Chilli Heat.

The aim of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. They are typically requested by practitioners and policymakers in order to guide their decisions. They can also be a great method of determining the causal relationship between an intervention and its results. They should not, however, be used to replace explanatory studies.

The pragmatism idea is controversial and there are doubts regarding whether pragmatic trials could be used to replace explanation tests or if they should be a complement to them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which confirm a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, that inform the practice and policy decision-making. They also proposed an approach to pragmatic trials, called PRECIS.2 This tool attempted to define the characteristics of a pragmatic trial which includes recruitment, design and delivery of the intervention, and the follow-up.

The number of pragmatic trials is growing. A recent Medline search using the keywords naturalistic and pragmatic, limited to controlled trials that are randomized (RCTs) produced 34 articles, which are shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to keep in mind that the majority of these studies were conducted in primary care settings.