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Clinical trials that are designed to help inform practice in the real world are referred to as pragmatic trials. They are often focused on the practical aspects of research design, like the recruitment process and consent as well as adherence to the use of standard equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used various investigators and had participants from different geographic areas. This kind of heterogeneity is necessary for pragmatic trials to be able to prove their validity, and it also helps reduce bias in the results. However too much heterogeneity could lead to problems with the design of the trial.

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Pragmatic trials are designed to replicate real-life situations and attain maximum external validity. They are usually requested by policy makers and practitioners to inform their decision making. They can also be a great way to identify the causal relationship between an intervention and its results. However, they should not be used in lieu for the use of explanation studies.

The pragmatism idea is controversial and there are concerns about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which confirm the physiological hypothesis or clinical hypothesis, 무료슬롯 프라그마틱 and pragmatic trials, that inform the decision-making process for policy and practice. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool attempted to define the traits of a pragmatic research study, including recruitment, design, delivery of the intervention and its follow-up.

The number of pragmatic trials is growing. A recent Medline query using the keywords pragmatic and 프라그마틱 카지노 naturalistic, limited to randomised controlled trials (RCTs) returned 34 articles. These are highlighted in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. However, it is important to keep in mind that the majority of these trials were conducted in primary care settings.