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Pragmatic trials are those that are designed to provide information for real-world clinical practice. They are often characterized as focusing on practical aspects of study design which include recruitment and consent, adherence and the use of routinely available equipment.
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A pragmatic study that involves various investigators and 무료슬롯 프라그마틱 participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity which is vital for pragmatic trials to be reliable and reduce bias in results is also essential. However excessive heterogeneity could cause issues with the design of the trial.
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The goal of pragmatic trials is to simulate real-life scenarios and gain the highest level of validity externally. They are usually requested by practitioners and policy makers to inform their decision making. They can be used to determine the causality of an intervention and its effects. However, they should not, be used to replace explanatory studies.
The concept of pragmatism is controversial, and there are doubts about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which prove the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, 프라그마틱 불법 이미지 - visit this web page link - which inform the decision-making process for policy and practice. They also suggested an approach to pragmatic trials, dubbed PRECIS.2 This tool attempted to define the features of a pragmatic trial, including the recruitment process, the design and implementation of the intervention, and the follow-up.
There is an encouraging trend in the number of pragmatic trials that are published. A recent Medline search using the keywords pragmatic and naturalistic, restricted to controlled trials randomized to control (RCTs) produced 34 articles, shown in red in Figure 2. This is a sign that the health science community is becoming increasingly sensitized to the issue of pragmatism. It is important to keep in mind that the majority of these trials were conducted in primary care settings.