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Pragmatic trials are studies designed to provide information for the real-world practice of clinical. They are typically described as focusing on practical aspects of design, including recruitment and consent, adherence and the use routinely available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and participants from various geographical areas. This type of heterogeneity, which is vital for a pragmatic trial to be valid and lessen the chance of bias, is also necessary. However excessive heterogeneity could lead to problems with the design of the trial.

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Pragmatic Play has earned a name for itself by providing high-quality games and a superior user experience. Its software is designed to work with mobile devices and is compatible with various languages. It has established itself as one of the most popular gaming platforms in the casino industry despite its relatively young age. Wolves is one of its latest releases, a 5-reel slot machine with a healthy RTP and stunning graphics. The other notable titles include Wolf Gold and Chilli Heat.

The purpose of pragmatic trials is to simulate real-life scenarios and to achieve maximum credibility externally. They are usually commissioned by policy makers and practitioners to guide their decision-making. They are also a good way to identify the cause-effect relationship between an intervention and its outcomes. They should not, however be used to replace explanation studies.

The concept of pragmatism is controversial, and there are questions regarding whether pragmatic trials could replace explanatory tests or if they should be an addition to them. Schwartz and Lellouch1 suggested the distinction between explanation studies, 프라그마틱 슬롯 (Http://Bridgehome.Cn/Copydog/Home.Php?Mod=Space&Uid=1783136) which prove a physiological hypothesis or clinical hypothesis, and pragmatic trials, that inform policy and practice decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the elements of a pragmatic research study that includes recruitment, design, delivery of the intervention and its follow-up.

The number of pragmatic trials is growing. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs), yielded 34 articles, which are shown in red in Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to note that the majority of these trials were conducted in primary care settings.