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Pragmatic trials are trials designed to provide information for the practice of clinical trials in real life. They are usually characterized by a focus on the practical aspects of study design, including recruitment and consent as well as adherence to the use of commonly available equipment.
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Pragmatic is a software development company that offers a wide range of casino games available on online gambling platforms. Its iGaming software is used by leading operators as well as casinos that are located in the land. The company provides front-end design tools, analysis, marketing, promotions payment systems, security, customer service and bug reporting. Additionally, the company provides its players a safe and secure environment with high-quality graphics and games.
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A pragmatic trial that uses various investigators and participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is necessary for practical trials to be valid and also reduces bias in the results. A high degree of heterogeneity, however can result in problems with the design of the trial.
Pragmatic Play is also a major player on the live casino market, offering an array of table games that are classic such as Blackjack and Roulette in various versions. Pragmatic Play's live studios in Romania and Malta provide a genuine gaming experience for its customers and offer a full suite of virtual betting options. The company has also developed several interactive game shows to make online gambling enjoyable. Some of these shows are telecast live and some feature famous personalities in the industry.
Mobile compatibility
Pragmatic Play is a relatively new player in the world of online casinos however, it has already established itself through its mobile-friendly slot machines. Their games are optimized for mobile devices and operate on HTML5 technology. They're also certified by reputable gaming authorities to ensure fairness and transparency. This is a good indication for players as it means that the games are tested and verified to ensure that the results of each round are random and fair.
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Legality
Pragmatic Play has earned a reputation for providing high-quality games and a superior user experience. Its software is accessible on mobile devices and in a variety of languages. It has been recognized as one of the leading gaming platforms in the casino industry despite its relative infancy. Wolves is one of the latest games that is a 5-reel slot machine with a hefty RTP and impressive graphics. Its other notable titles are Wolf Gold and Chilli Heat.
The purpose of pragmatic trials is to simulate real-life scenarios and to achieve the highest level of validity externally. They are usually commissioned by policy makers and practitioners to aid in their decision-making. They can also be used to determine the causal relationship between an intervention and its results. However, they should not be used in lieu for explanation trials.
The pragmatism idea is controversial, and there are questions regarding whether pragmatic trials could replace explanatory tests or if they should serve as an alternative to them. Schwartz and Lellouch1 made a distinction between explanatory studies, which confirm the validity of a physiological or clinical hypothesis, and pragmatic trials that aid in policy and practice decision-making. They also suggested the framework for pragmatic trials, called PRECIS.2 This tool was designed to define the elements of a pragmatic study which includes the recruitment process, the design and implementation of the intervention, and monitoring.
The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to randomized controlled trials (RCTs) produced 34 articles, shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. It is important to keep in mind that the majority of these trials were conducted in primary care settings.