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Studies designed to provide insight into clinical practice in the real world are referred to as pragmatic trials. They are typically described by their focus on practical aspects of study design, including recruitment and consent, adherence and the use of standard equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and participants from different geographic areas. This type of heterogeneity is required for practical trials to be valid, and it also helps reduce the chance of bias in the results. However too much heterogeneity could cause problems with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. They are typically commissioned by policymakers and practitioners to help inform their decisions. They can be used to determine the causality of an intervention and its results. However, they should not be used to substitute for 프라그마틱 슬롯 하는법 무료 프라그마틱체험 (look at more info) explanatory trials.

The idea of pragmatism is controversial, and there are questions about whether pragmatic trials can replace explanatory tests or if they should be an addition to them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which validate the validity of a clinical or physiological hypothesis as well as pragmatic trials, which guide the policy and practice of. They also proposed a framework called PRECIS for pragmatic trials.2 This tool tried to define the elements of a practical study which includes the recruitment, design, and delivery of the intervention and its follow-up.

The number of pragmatic trials is growing. A recent Medline search using the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to note that the majority of these studies were conducted in primary care settings.