The Mesothelioma And Asbestos Case Study You ll Never Forget
Mesothelioma and Asbestos
Asbestos, a natural mineral, occurs naturally in the form of long, thin fibers. People who are regularly exposed to asbestos may develop lung diseases like mesothelioma.
It could take a long time before symptoms begin to manifest after exposure to asbestos. Different asbestos types can cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma is a cancer that occurs in the outer lung the lining (pleura). It is the most prevalent mesothelioma form and is responsible for 70 to 79% all diagnosed cases. People with this condition suffer from chest pain and breathlessness and may also feel a sensation of heaviness in the chest.
Exposure to asbestos, a family of minerals comprised of microscopic fibers, usually causes this kind of cancer. Once inhaled, these fibers cling to the lungs and cause irritation that causes scarring and DNA mutations. Pleura surrounds both the chest cavity and the lungs, and so irritations can also affect the heart. Mesothelioma usually doesn't show symptoms until 30 to 50 year after exposure.
Shortness of breath and chest pain are the most common symptoms. Patients may also experience difficulty breathing, or chest tightness. People who suffer from this cancer usually have a history of exposure to asbestos in the workplace. The most prevalent jobs that put people at risk of pleural mesothelioma include manufacturing, construction, and shipbuilding. Individuals who have been in the military may be at risk because of the extensive asbestos case use in Navy vessels and army bunkers.
The most popular staging system for pleural mysothelioma has been the TNM (tumor lymph nodes, lymph nodes and metastases) staging system. The stage that the patient is in at the time of diagnosis will help determine what treatment plan they should follow. Patients who have pleural mesothelioma which is in stage three or stage four will suffer a more negative prognosis than those in a lower stage. Stage four mesothelioma may develop into the heart, liver or diaphragm. This could make the cancer more difficult to treat and increase the risk of complications for the patient.
Peritoneal Mesothelioma
In contrast to pleural mesothelioma which is a lung-lining cancer, peritoneal mesothelioma develops in the peritoneum -- a membrane that lines the abdominal cavity as well as organs like the liver and intestines. Similar to pleural mesothelioma mesothelioma can be caused by asbestos exposure. The disease is much less prevalent than pleural mesothelioma, with only about 300-500 cases diagnosed each year.
As with pleural asbestosis, symptoms can take several years to show. Patients typically suffer from abdominal pain and may also have a lump in their abdomen. This kind of mesothelioma can cause nausea, weight loss, and fever. Many of these symptoms are similar to symptoms of digestive problems, which can cause misdiagnosis.
Doctors can identify mesothelioma by examining the patient's medical history and conducting a physical exam. They may also employ imaging tests like X-rays, CT scans and PET/CT scans to help find mesothelioma. These tests can show tumors and other symptoms of cancer that aren't apparent on an X-ray.
These test results allow doctors to diagnose mesothelioma and determine the stage of the disease and suggest treatment options. The stage is determined by the type of cell and whether the cancer has spread.
Asbestos exposure is the main risk factor. People who have worked in asbestos-related occupations, like electrical or plumbing work or in construction and manufacturing are more likely to contract the disease. Even if a person does not work in one of these fields they could still be exposed to asbestos through family members and other sources. For this reason, anyone who suspects they may be at risk should talk to an expert. A mesothelioma specialist can help those who have a experience with asbestos to understand more about their risk.
Risk Factors
Asbestos is the most significant risk factor for mesothelioma. It accounts for up to 80percent of cases. Exposure to asbestos may occur through work, military service, or living with those who worked with asbestos claim. When exposed to asbestos, small particles can be breathed into the lungs and abdomen. These particles can cause irritation to the linings and cause cancerous cells to develop in the mesothelium. After asbestos exposure mesothelioma is likely to develop between 15 and 60 year.
Other risk factors include smoking, genetics and the advancing age. People in their 40s or 50s are at a higher risk of developing mesothelioma compared to people who are younger or more. It takes mesothelioma between 20 and 60 years to show signs of cancer after the first exposure. It is important to remember, too, that mesothelioma may occur in people who have been exposed to Asbestos case, but without having been directly exposed to it. This is referred to as indirect or secondary asbestos exposure. It can be as dangerous as direct asbestos claim exposure.
Smoking increases a person's chances of getting mesothelioma because it damages the mesothelium and makes it more prone to asbestos. Mesothelioma is also aggravated by certain illnesses, including asbestosis and pneumonia. Men are more likely to develop mesothelioma than females. This is because men are more likely to work with asbestos and have more exposure than women. Men are also more likely to have lived with someone who had worked with asbestos, and to have asbestos-containing fibers on their clothing. Women are less likely to come into contact with asbestos and don't typically carry asbestos on their clothes.
Diagnosis
It is difficult to recognize mesothelioma due to its symptoms being frequently similar to other illnesses. This could lead to patients being incorrectly diagnosed.
The first step in diagnosing mesothelioma is for NYU Langone doctors to perform an examination and write down a patient's medical history including asbestos exposure. Doctors can also order an X-ray chest or CT scan to look for lumps and other abnormalities, and also to look for evidence of past asbestos exposure such as pleural plaques (thickened pleura with calcium deposits) and the formation of fluid between the lung and the chest wall (known as the pleural effusion).
Other diagnostic tests include an echocardiogram which examines the heart and blood vessels and magnetic resonance imaging, or MRI, test, which uses radio waves and magnets to make a series of detailed images of the inside of the body. A surgical biopsy is yet another way for doctors to diagnose mesothelioma. During a surgery biopsy doctors will remove a small part of tissue from the pleura or the peritoneum, to be examined further. A pathologist will then look at the tissue with a magnifying glass to determine whether it contains cancerous cell.
The type of mesothelial cells involved, the malignant or benign nature of those cells and the location, type and stage of the tumour, are used to classify the disease. Certain types of mesothelioma are more likely to develop metastasis or spread and spread, therefore it is essential to get a definite diagnosis to ensure that doctors are able to treat the disease before it goes out of control.
Doctors may also conduct tests in the laboratory on tumors to determine specific proteins, genes or other elements that can aid in describing cancer characteristics and determine the best treatment. These results are referred to as staging.
Treatment
A mesothelioma diagnosis is a frightening prospect. It is important to keep in mind that cancer can be treated, particularly in its early stages. Many patients with mesothelioma endure the disease for a long time, without expanding.
Exposure to asbestos can trigger mesothelioma via various mechanisms. Asbestos fibres, small enough to not be felt or seen by naked eyes, can become airborne, irritating the lung's lining (pleura). In time the irritation can lead to the formation of scar tissue and eventually tumors.
The Pleura is a covering that covers the abdomen, heart, and lungs. Mesothelium consists of cells that react when exposed to asbestos. They cause inflammation to the tissue and cause it to scar. In time, these changes can cause the development of malignant mesothelioma tumors.
A shortness of breath, chest discomfort or fluid buildup on the lungs are all indications of the pleural mesothelioma. In rare instances cancer may spread to the tissues around the reproductive organs and heart.
If scans of imaging reveal an area of concern in the lungs or stomach, a doctor will order biopsies. The procedure involves the removal of a small amount of fluid or tumor to allow for laboratory testing. The results can confirm the diagnosis of mesothelioma and determine the best treatment option.
There are several types of mesothelioma treatment, including chemotherapy, surgery and immunotherapy. Most doctors utilize an amalgamation of these techniques. Patients may also benefit from taking part in a clinical trial of new mesothelioma treatments. To learn more, patients should speak to a mesothelioma specialist who has had experience treating the disease.