The Mesothelioma And Asbestos Case Study You ll Never Forget
Mesothelioma and Asbestos
Asbestos is a naturally occurring mineral that is made up of thin, long fibres. People who are exposed to asbestos risk developing lung diseases such as mesothelioma.
It could take a long time before symptoms begin to manifest after asbestos exposure. Different asbestos case (this content) types may cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma is a cancer of the lung's outer lining or the pleura. It is the most frequent mesothelioma type and accounts for 70% to 79% of diagnosed cases. Patients with this disease experience pain in the chest and breathlessness, and they may feel the sensation of weight in the chest.
Exposure to asbestos, a group of minerals comprised of microscopic fibers, usually causes this kind of cancer. Once inhaled, these fibers are absorbed into the lung and cause irritation that leads to scarring and DNA mutations. Pleura surrounds both the chest cavity and the lungs, so irritations can also affect the heart. Mesothelioma is usually not symptomatic until 30 to 50 year after exposure.
The most frequent symptoms of pleural mesothelioma include chest discomfort and shortness of breath. Some patients also experience coughing, difficulty breathing, or chest tightness. Patients with this cancer have a past that includes asbestos exposure at work. The most common jobs that expose workers to the risk of developing pleural cancer are construction, manufacturing and shipbuilding. People who served in the military are at a greater risk due to the widespread use of asbestos in Navy vessels and bunkers for the Army.
The TNM (tumors, lymph nodes, and metastases staging system) is the most popular staging system used to treat pleural adenocarcinoma. The stage that a patient is in at the time of diagnosis can help determine what treatment plan they should follow. For instance, patients suffering from mesothelioma that is pleural in stage three or four have a less favorable prognosis than patients with lower stages. Stage four mesothelioma can develop into the liver, heart or diaphragm. This makes it more difficult to treat and increases the risk of complications for the patient.
Peritoneal Mesothelioma
Unlike pleural cancer, that develops in the lining of the lung it develops in the membrane that covers the abdominal cavity, which includes organs like the intestines and the liver. Like pleural mesothelioma, asbestos exposure is the reason for peritoneal msothelioma. Only 300-500 cases are diagnosed annually this is less than pleural asbestosis.
As with pleural mesothelioma symptoms can take a long time to manifest. Patients usually have abdominal pain, and could also experience a mass in their abdomen. The symptoms of this kind of mesothelioma can also include nausea, weight loss and fever. A lot of these symptoms can be misinterpreted as digestive issues which can lead to a misdiagnosis.
The doctors can detect mesothelioma through reviewing the medical history of the patient and performing a physical examination. They can also use imaging tests such as X-rays, CT scans and PET/CT scans to identify mesothelioma. These tests can show cancerous tumors or other indications of cancer that aren't apparent on an X-ray.
These tests enable doctors to diagnose mesothelioma and determine the stage and recommend treatment options. Staging is determined based on the type of cells and whether or the tumor has spread to other regions of the body.
Asbestos exposure is the biggest risk factor. People who have worked in jobs that involve asbestos, like plumbing or manufacturing, electrical work, or construction, are at increased risk of developing the disease. However, even if individuals aren't employed in these areas they could be exposed to asbestos through family members or other sources. This is why anyone who believes they could be at risk should speak to an expert. A mesothelioma specialist can help those who have a experience with asbestos to understand more about their risk.
Risk Factors
Asbestos is the most significant risk factor in mesothelioma. It is responsible for up to the 80% of cases. Exposure to asbestos claim may occur due to military service, work or living with those who worked with asbestos. When exposed to asbestos, particles can be breathed into the lungs and abdomen. These particles can cause irritation to the linings and trigger cancerous cells to grow in the mesothelium. Mesothelioma can take between 15 and 60 years to develop following exposure to asbestos.
Other risk factors include smoking, genetics and aging. People in their 40s and 50s are more at risk of developing mesothelioma compared to those younger or older. It is because mesothelioma generally occurs between 20 and 60 years from the first exposure before cancer symptoms appear. It is also important to note that mesothelioma is a possibility in people who were exposed to asbestos but did not work with it directly. This is referred to as secondary or indirect exposure to asbestos. It could be as hazardous as direct exposure.
Smoking can increase the likelihood of getting mesothelioma because it damages the mesothelium and makes it more susceptible to asbestos. Mesothelioma can also be aggravated by certain diseases, such as asbestosis and pneumonia. Men are more likely to develop mesothelioma than women. This is because men are more likely to work with asbestos and experience a more exposure than women. Men are also more likely to have lived with someone who had worked with asbestos and to have asbestos fibers on their clothing. Women tend to have less contact with asbestos and don't typically carry asbestos on their clothing.
Diagnosis
It is difficult to recognize mesothelioma due to its symptoms being often similar to other conditions. This can lead to victims being wrongly diagnosed.
NYU Langone doctors will perform physical examinations and document the patient's medical history, including asbestos exposure. Doctors may also request a CT scan or chest X-ray to look for lumps, abnormalities, and evidence of exposure to asbestos. These include plaques in the pleura, thickened pleura and calcium deposits.
Other diagnostic tests include an echocardiogram which examines the heart and blood vessels, and a magnetic resonance imaging, also known as MRI, test, which uses magnets and radio waves to create precise images of the inside of the body. Another way for doctors to detect mesothelioma is through a surgical biopsy. In a surgical biopsy doctors will remove a small piece of tissue from the pleura or the peritoneum to be tested further. A pathologist will then look at the tissue using a magnifying lens to determine if it contains cancerous cell.
Mesothelioma can be classified based on the type of mesothelial cell involved, whether these cells are benign or malignant and also the location of the tumor, its type, and the stage of the cancer. Certain types of mesothelioma may be more likely to grow or spread, so it is important to establish a definitive diagnosis so doctors can treat the disease before it gets out of control.
Doctors can also perform tests in the lab on tumors in order to determine specific genes, proteins or other factors that can help them describe the characteristics of cancer and plan treatment. These results are called staging.
Treatment
A diagnosis of mesothelioma can be terrifying. It is important to keep in mind that cancer can be treated especially at its early stages. Many people with mesothelioma live for many years without the disease spreading to other areas of their body.
Exposure to asbestos can cause mesothelioma by many mechanisms. asbestos attorney fibers that are small enough to not be felt or viewed by naked eyes can be airborne, causing irritation to the lung's lining (pleura). In time irritation can lead to formation of scar tissue which leads to changes in the cell structure which eventually lead to tumors.
The pleura surrounds the heart and lungs, as well as the abdomen. Mesothelium consists of cells that respond when exposed to asbestos. They inflame the tissue and cause it to scar. Overtime, these changes cause the development of malignant mesothelioma tumors.
The symptoms of pleural mesothelioma are breathing problems, chest pain or an accumulation of fluid on the lungs (pleural effusion). In rare instances the cancer may be spread to the tissues around the heart and reproductive organs.
A doctor will request a biopsy if imaging scans reveal a possible mass in the lungs or stomach. During the procedure, doctors take small amounts of the tumor or fluid for lab analysis. The results will confirm the diagnosis of mesothelioma, and also determine the best treatment plan.
There are several types of mesothelioma treatment, including chemotherapy, surgery and immunotherapy. Most doctors utilize an amalgamation of these techniques. Patients can also benefit by participating in a clinical study of new mesothelioma treatment. Patients can learn more by consulting a mesothelioma specialist who has treated the disease.