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Clinical trials that are designed to help inform practice in the real world are referred to as pragmatic trials. They are often described as a focus on the practical aspects of designing a study which include the recruitment and consent process, as well as adherence and 라이브 카지노 the use routinely available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and included participants from different geographical regions. This type of heterogeneity, which is vital for a pragmatic trial to be valid and reduce bias in results is also essential. However, too much heterogeneity can result in problems with the design of the trial.

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Pragmatic trials are designed to replicate real-world situations and have the highest external validity. Usually, they are commissioned by policymakers and practitioners to help inform their decisions. They also provide a useful way to identify the causal relationship between an intervention and its results. However, they should not, be used to replace the need for explanation studies.

The pragmatism concept is controversial and there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which prove the validity of a physiological or clinical hypothesis, as well as pragmatic trials, which inform policy and practice decision-making. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool tried to define the elements of a pragmatic research study which includes the recruitment, design, and delivery of the intervention and its follow-up.

There is an encouraging trend in the number of pragmatic trials that are published. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs) produced 34 articles, shown in red in Figure 2. This indicates that the health sciences community is becoming more sensitive to the issue of pragmatic thinking. It is important to keep in mind, however, that the majority of these studies were conducted in primary care settings.