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Pragmatic trials are those that are designed to provide information for the real-world practice of clinical. They are often described as focusing on practical aspects of designing a study which include the recruitment and consent process, as well as adherence and the use routinely available equipment.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and included participants from various geographical areas. This type of heterogeneity which is essential for a pragmatic trial to be reliable and 프라그마틱 사이트 reduce bias in results is also essential. A high degree of heterogeneity, however can result in problems with the design of the trial.
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The purpose of pragmatic trials is to simulate real-life situations and achieve maximum credibility externally. They are usually requested by practitioners and policy makers to aid in their decision-making. They are also a good method of determining the cause-effect relationship between an intervention and its outcomes. They should, however, not, be used to replace explanatory studies.
The pragmatism concept is controversial and there are concerns about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove a physiological or clinical hypothesis as well as pragmatic trials that inform the policy and practice of. They also proposed a framework called PRECIS for pragmatic trials.2 This tool tried to define the characteristics of a pragmatic study that includes recruitment, design, delivery of the intervention and its follow-up.
The number of pragmatic trials is growing. A recent Medline query that used the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to keep in mind that the majority of these trials were conducted in primary care settings.