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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are usually characterized by a focus on the practical aspects of the study design, including the recruitment and consent process as well as adherence to the use of commonly available equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which utilized different investigators and had participants from different geographic areas. This kind of heterogeneity is necessary for practical trials to be valid and reduces bias in the results. A high degree of heterogeneity, however can result in problems with the trial design.

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Legality

Pragmatic Play is known for its top-quality games and also for providing an outstanding user experience. Its software can be used on mobile devices and in multiple languages. It has established itself as one of the most popular gaming platforms in the casino industry despite its relative youth. Wolves is one of the latest games, a 5-reel slot machine that has a high RTP and stunning graphics. Other notable games include Wolf Gold and Chilli Heat.

The goal of pragmatic trials is to replicate real-life situations and achieve the highest level of validity externally. They are usually commissioned by practitioners and policy makers to guide their decision-making. They are also a good method to determine the causal relationship between an intervention and its results. However, they should not be used to substitute for explanatory trials.

The pragmatism idea is controversial and there are concerns about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 made the distinction between explanation studies, which support the validity of a physiological or clinical hypothesis, and pragmatic trials, that inform the decision-making process for 프라그마틱 슬롯 무료체험 policy and practice. They also suggested a framework for pragmatic trials, called PRECIS.2 This tool sought to define the features of a pragmatic study which includes recruitment, design and delivery of the intervention, and follow-up.

The number of pragmatic trials is growing. A recent Medline query using the keywords pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. These are highlighted in red on Figure 2. This is an indication that the health sciences community is becoming increasingly sensitized to the issue of pragmatic thinking. It is important to keep in mind, however, that the majority were conducted in primary-care settings.