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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are often characterized as a focus on the practical aspects of design, including the recruitment process and consent, adhering and the use of standard equipment.
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A pragmatic study that involves different investigators and participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity that is crucial for 무료 프라그마틱 pragmatic trials to be reliable and lessen the chance of bias is also essential. A high degree of heterogeneity, however, can cause problems with the design of the trial.
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The aim of pragmatic trials is to replicate real-life situations and achieve maximum credibility externally. They are typically commissioned by policymakers and practitioners to inform their decisions. They can also be used to determine the cause-effect relationship of an intervention and its results. However, they should not be used to substitute for explanation trials.
The concept of pragmatism is controversial, and there are questions regarding whether pragmatic trials could be used to replace explanation tests or if they should serve as an alternative to them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove a physiological or clinical hypothesis and 프라그마틱 정품 이미지 (https://socialmediainuk.com/story19150680/comprehensive-list-of-pragmatic-return-rate-dos-and-don-ts) pragmatic trials that inform the practice and policy decisions. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the elements of a pragmatic study, including recruitment, design, delivery of the intervention and its follow-up.
There is an encouraging increase in the number pragmatic trials that have been published. A recent Medline search using the keywords naturalistic and pragmatic, limited to controlled trials that are randomized (RCTs) produced 34 articles, as shown in red in Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to keep in mind that the majority of these studies were conducted in primary care settings.