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Pragmatic trials are trials designed to provide information for the real-world practice of clinical. They are typically described as focusing on practical aspects of designing a study which include recruitment and consent, adherence and the use of standard equipment.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized a variety of investigators and participants from different geographic areas. This type of heterogeneity which is essential for a pragmatic trial to be valid and to reduce bias in the results, is also necessary. Too much heterogeneity, however can result in problems with the trial design.
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The purpose of pragmatic trials is to replicate real-life scenarios and gain maximum validity externally. They are typically commissioned by policy makers and practitioners to inform their decision making. They can also be a great method to determine the causality between an intervention and its results. However, they shouldn't be used to substitute for explanatory studies.
The pragmatism idea is controversial and 프라그마틱 무료스핀 there are doubts regarding whether pragmatic trials could replace tests for explanations or if they should be an alternative to them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove the validity of a clinical or physiological hypothesis, and pragmatic trials, which guide the practice and policy decisions. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool tried to define the characteristics of a practical study that includes the recruitment, design, and delivery of the intervention and its follow-up.
There is a positive increase in the number of pragmatic trials published. A recent Medline search using the terms pragmatic and naturalistic, restricted to randomized controlled trials (RCTs) produced 34 articles, as shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. It is important to remember, however, that the majority of these studies were conducted in primary care settings.