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Pragmatic trials are those that are designed to inform the practice of clinical trials in real life. They are usually characterized by a focus on practical aspects of the study design, including recruitment and consent, adherence, and the use of routinely available equipment.

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A pragmatic study that involves a variety investigators and includes participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is necessary for practical trials to be valid and also reduces the chance of bias in the results. A high degree of heterogeneity, however, can cause problems with the trial design.

Pragmatic Play Pragmatic Play, a major player on the live casino market, provides various classic table games such as Blackjack and Roulette. The live studios of Pragmatic Play in Romania and Malta provide customers with an authentic gaming experience as well as a broad variety of betting options via virtual. The company has also created various interactive games to make online gambling fun. Some of these shows feature live hosts, while others are hosted by famous personalities from the industry.

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Pragmatic trials aim to mimic real-life settings and achieve maximum external validity. They are usually requested by practitioners and policy makers to inform their decision making. They can also be a great method to determine the causal relationship between the intervention and 무료슬롯 프라그마틱 its effects. However, they should not be used as a substitute for explanatory studies.

The idea of pragmatism is controversial and there are doubts about whether pragmatic trials should be used to replace explanation tests or if they are a complement to them. Schwartz and Lellouch1 made the distinction between explanation studies, which support a physiological hypothesis or clinical hypothesis, and pragmatic trials, that inform policy and practice decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the traits of a pragmatic study which includes recruitment, design, delivery of the intervention and its follow-up.

There is an encouraging increase in the number of pragmatic trials published. A recent Medline search using the terms pragmatic and naturalistic, restricted to randomized controlled trials (RCTs), yielded 34 articles, shown in red in Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to note, however, that the majority of these studies were conducted in primary-care settings.