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Studies designed to provide insight into clinical practice in the real world are referred to as pragmatic trials. They are typically characterized by a focus on the practical aspects of study design, including the recruitment process and consent, 무료슬롯 프라그마틱 adherence, and the use of routinely available equipment.

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Pragmatic, a software company, offers a variety of casino games to online gambling platforms. Pragmatic's iGaming solutions are utilized by the most reputable operators as well as casinos that are located in the land. The company offers front-end website design tools, analysis tools and promotions, marketing, security, payment systems, customer support and bug-reporting. The company also offers security, high-quality graphics, games and security.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and included participants from various geographical areas. This type of heterogeneity which is essential for pragmatic trials to be reliable and to reduce bias in the results, is also necessary. However too much heterogeneity could cause problems with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. They are usually requested by policy makers and practitioners to inform their decision making. They can also be used to assess the causal relationship between an intervention and its effects. However, they should not be used as a substitute for explanatory trials.

The concept of pragmatism is controversial, and there are doubts about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which confirm a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform the practice and policy decision-making. They also proposed the framework for pragmatic trials, dubbed PRECIS.2 This tool attempted to define the features of a pragmatic study, including the recruitment process, the design and implementation of the intervention, as well as the follow-up.

The number of pragmatic trials is growing. A recent Medline search using the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs) returned 34 articles. These are highlighted in red on Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to keep in mind, however, that the majority of studies were conducted in primary care settings.